Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors inside the central nervous technique, conolidine modulates alternate molecular targets. A Science Advances analyze found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By infl... https://billd318xac0.law-wiki.com/user