Opana 40 mg is a powerful opioid that is used to control intense, constant pain in those who already have a tolerance to opioids. The high-strength formula should not be used in a limited manner and should be used only by those under medical supervision because of the potential for addiction, overdose, or respiratory depression.The normal dosage and frequency is determined by a doctor... https://medixfire.com/product/opana-er-40-mg/